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list of prohibited drugs

List of Prohibited Drugs

Is there a list of prohibited drugs for being medically qualified to drive a commercial motor vehicle (CMV)?

Section 391.41(b)(12) states: A person is physically qualified to drive a CMV if that person does not use a controlled substance identified in 21 CFR 1308.11, Schedule I, an amphetamine, a narcotic, or any other habit-forming drug. Exception: A driver may use such a substance or drug, if the substance or drug is prescribed by a licensed medical practitioner who is familiar with the drivers medical history and assigned duties; and has advised the driver that the prescribed substance or drug will not adversely affect the drivers ability to safely operate a CMV. This exception does not apply to methadone.

Medical Examiners are required to give careful consideration to the effects of medications on a drivers ability to operate a CMV safely before rendering the driver qualified.

For information on specific drugs and CMV driver qualification, please visit the Federal Motor Carrier Safety Administration's Medical Program website at: Questions about the effects of many drugs and driver qualification are answered in the Frequently Asked Questions (FAQs) section. You may also e-mail your questions to the Physical Qualifications Division at or call and ask for a Specialist on (202) 366-4001.

These responses do not substitute for the regulations found in 49 CFR Part 40 or any other DOT agency or United States Coast Guard (USCG) specific regulation. If you have a question about the DOT drug and alcohol testing program rules, read the regulatory text.

If you have any questions about drug testing regulations or our mobile drug testing services, call us today at 678-804-7225 or email us today.

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